VIT Blog

If you use the standard ASP.NET menu (or toolbar) in your web application, it works well in most browsers except for Safari & Chrome. In these 2 browsers, each menu item appears on a new line.

The fix I found was placing the following code in my MaterPage code-behind:
if (Request.UserAgent.IndexOf(“AppleWebKit”) > 0)
        {
            Request.Browser.Adapters.Clear();
        }

If you are not using a Materpage:
protected void Page_PreInit(object sender, EventArgs e)
    {
        if (Request.UserAgent != null && Request.UserAgent.IndexOf(“AppleWebKit”, StringComparer.CurrentCultureIgnoreCase) > -1)
        {
            this.ClientTarget = “uplevel”;
        }
    }

The solution is adapted from this site (Thank you):
http://weblogs.asp.net/joshuajohnson/archive/2008/01/23/how-do-i-overcome-the-dreaded-safari-asp-net-menu-conundrum.aspx